Reaction engineering and up-scaling of light-driven in vitro oxidative lactonizations

Fellow: ESR11
Home Institution: Aarhus University – Denmark
Academic Secondment 1: University of Graz (Karl-Franzens-Universität) – Austria
Academic Secondment 2: Technical University of Denmark – Denmark
Industrial Secondment: Chiracon GmbH – Germany


This research will focus on the:

i) Optimization of the ADH-catalyzed light-driven in vitro lactone synthesis;

ii) Reaction engineering of the ADH-catalyzed light-driven in vitro synthesis of lactones (bulk and fine chemicals);

iii) Evaluation of the photobiocatalytic lactone synthesis in terms of cost, productivity and sustainability;

iv) Up-scaling of the model reaction system for the synthesis of fine lactone.