Medium engineering of light-driven in vitro hydroxylations

Fellow: ESR12
Home Institution: Aarhus University – Denmark
Academic Secondment 1: Graz University of Technology  – Austria
Academic Secondment 2: Delft University of Technology – the Netherlands
Industrial Secondment: Chiracon GmbH – Germany


This research will focus on the:

(i) Investigation of the effect of organic solvents and process parameters on the light-driven in vitro redox-biocatalysis,

(ii) Evaluation of immobilization methods for biocatalytic light-driven hydroxylations,

(iii) Evaluation of the cosubstrates as reducing equivalents,

(iv) Up-scaling of the model reaction system at the industrial partner.